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Stratum plus. 2025. No2

A. V. Engovatova (Moscow, Russian Federation), A. A. Kanapin, A. A. Samsonova (Saint Petersburg, Russian Federation), Kh. Kh. Mustafin, I. E. Alborova, O. Yu. Chechyotkina, S. V. Vasiliev, M. B. Mednikova (Moscow, Russian Federation)

Identification of Ancient Pathogens: Streptococcus pneumoniae in DNA Samples from Four Burials of the Volosovo-Danilovsky Burial Ground of the Fatyanovo Culture




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Pages:  155-174 | DOI: https://doi.org/10.55086/sp252155174


This article advances a series of publications dedicated to the paleogenetic study of individuals from the Fatyanovo culture. Whole-genome sequencing of new samples from the Volosovo-Danilovsky burial ground in the Yaroslavl region of European Russia, along with rigorous bioinformatics analysis, has unequivocally demonstrated a significant genetic affinity between these individuals and the Bronze Age populations of the Czech Republic, Germany, and Great Britain, particularly those associated with the Bell Beaker and Pre-Unetice cultures. Moreover, a strong connection has been established with representatives from the Sintashta culture in the Ural region. Notably, for the first time, high-throughput sequencing data of ancient DNA has successfully identified potential ancient DNA of the pulmonary pathogen Streptococcus pneumoniae within the Bronze Age population of the Russian Plain of discernible migrant origin. The presence of this microorganism in all four cases, albeit at different levels, is an “incidental finding”, which allows us to speak of the need for further studies of samples from both the Volosovo-Danilovsky burial and other Fatyanovo sites, including the assessment of the prevalence of pathogenic microorganisms in the population of the Russian Plain at this time.


Keywords: Bronze Age, migrations, whole genome sequencing, infections, bioinformatics


Information about authors:

Asya Engovatova (Moscow, Russian Federation). Candidate of Historical Sciences. Institute of Archaeology of the Russian Academy of Sciences. Dmitry Ulyanov St., 19, Moscow, 117292, Russian Federation
E-mail: [email protected]
ORCID: 0000-0003-3109-2764

Alexander Kanapin (Saint Petersburg, Russian Federation). PhD. Institute of Translational Biomedicine, St. Petersburg State University. Universitetskaya Embankment 7/9, St. Petersburg, 199034, Russian Federation
E-mail: [email protected]
ORCID: 0000-0001-9802-5297

Anastasia Samsonova (Saint Petersburg, Russian Federation). PhD. Institute of Translational Biomedicine, St. Petersburg State University. Universitetskaya Embankment 7/9, St. Petersburg, 199034, Russian Federation
E-mail: [email protected]
ORCID: 0000-0002-9353-9173

Kharis Mustafin (Moscow, Russian Federation). Candidate of Technical Sciences. Moscow Institute of Physics and Technology. Institutsky Lane, 9, Dolgoprudny, 141701, Moscow Oblast, Russian Federation
E-mail: [email protected]
ORCID: 0000-0001-8891-2319

Irina Alborova (Moscow, Russian Federation). Candidate of Biological Sciences. Moscow Institute of Physics and Technology. Institutsky Lane, 9, Dolgoprudny, 141701, Moscow Oblast, Russian Federation
E-mail: [email protected]
ORCID: 0000-0002-1950-3885

Chechyotkina Olga (Moscow, Russian Federation). Institute of Archaeology of the Russian Academy of Sciences. Dmitry Ulyanov St., 19, Moscow, 117292, Russian Federation
E-mail: [email protected]
ORCID: 0000-0002-4880-1080

Sergey Vasilyev (Moscow, Russian Federation). Doctor of Historical Sciences. N. N. Miklukho-Maklai Institute of Ethnology and Anthropology, Russian Academy of Sciences. Lenin Ave., 32-A, Moscow, 119991, Russian Federation
E-mail: [email protected]
ORCID: 0000-0003-0128-6568

Maria Mednikova (Moscow, Russian Federation). Doctor of Historical Sciences, Candidate of Biological Sciences. Institute of Archaeology of the Russian Academy of Sciences. Dmitry Ulyanov St., 19, Moscow, 117292, Russian Federation
E-mail: [email protected]
ORCID: 0000-0002-1918-2161

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